EIDD-1931 | SARS-CoV-2 inhibitor | Probechem Biochemicals

Chemical Structure : EIDD-1931

CAS No.: 3258-02-4

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EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC)

货号: PC-72069Not For Human Use, Lab Use Only.

EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC) is an active metabolite of EIDD-2801 with broad-spectrum antiviral inhibitor of SARS-CoV-2.

规格	价格	库存
50 mg	￥880	In stock
100 mg	￥1280	In stock
250 mg	￥2180	In stock
1 g		Get quote

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生物&药学活性

EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC) is an active metabolite of EIDD-2801 with broad-spectrum antiviral inhibitor of SARS-CoV-2.
EIDD-1931 displays broad spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and related zoonotic group 2b or 2c Bat-CoVs with average IC50 of 0.15 μM, as well as increased potency against a coronavirus bearing resistance mutations to the nucleoside analog inhibitor remdesivir.

物理化学性质&存储条件

分子量	259.218
分子式	C9H13N3O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
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Solubility	10 mM in DMOS
Chemical Name/SMILES	1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one

参考文献

1. Painter WP, et al. Antimicrob Agents Chemother. 2021 Mar 1;65(5):e02428-20.

2. Sheahan TP, et al. Sci Transl Med. 2020 Apr 29;12(541):eabb5883.

EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC)

生物&药学活性

物理化学性质&存储条件

参考文献

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