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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-ROCK

Request The Product List ofROCK ROCK

Cat. No. Product Name Information
PC-43437

Thiazovivin

ROCK inhibitor

Thiazovivin is a small molecule inhibitor of ROCK, dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts.
PC-62716

Netarsudil dihydrochloride

ROCK inhibitor

Netarsudil (AR-13324) dihydrochlorideis a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2.
PC-62715

Verosudil

ROCK inhibitor

Verosudil (AR-12286) is a potent ROCK inhibitor with Ki of 2 nM for both ROCK1 and ROCK2.
PC-62714

Netarsudil

ROCK inhibitor

Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2.
PC-61252

FPND

ROCK1 inhibitor

FPND (FPMINT) is a novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2, also is an inhibitor of equilibrative nucleoside transporter ENT1 and ENT2.
PC-60681

PF-4950834

ROCK inhibitor

PF-4950834 is a potent, selective, ATP-competitive and orally acitve Rho kinase (ROCK) inhibitor with IC50 of 33.1 and 8.5 nM for ROCK1 and ROCK2, respectively.
PC-42669

Y-27632 dihydrochloride

ROCK1 inhibitor

Y-27632 dihydrochloride is a potent, selective ROCK1 (p160 ROCK) inhibitor with Ki of 140 nM in cell-free assay.
PC-42232

Y-27632

ROCK inhibitor

Y-27632 (Ninvosudil, Y27632) is a potent, selective ROCK1 (p160 ROCK) and ROCK2 inhibitor with Ki of 220 nM and 300 nM in cell-free assays.
PC-42519

BAY-549

ROCK inhibitor

A potent, highly selective, ATP-competitive ROCK inhibitor with IC50 of 0.5/1.1 nM for ROCK1/ROCK2 respectively.
PC-44656

H-1152

ROCK inhibitor

H-1152 is a potent and selective ROCK inhibitor with Ki of 1.6 nM.
PC-42222

Y-39983

ROCK inhibitor

Y-39983 (Y-33075 hydrochloride) is a potent and selective p160 ROCK inhibitor with Ki of 140 nM.
PC-42541

Fasudil

ROCK inhibitor

Fasudil (AT-877, HA-1077) is a potent and selective inhibitor of Rho kinase (ROCK) with Ki of 0.33 uM (ROCK1).

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