| Cat. No. |
Product Name |
Information |
| PC-27410 |
Bazipsudil
ROCK inhibitor
|
Bazipsudil is a potent, selective Rho-associated protein kinase (ROCK) inhibitor. |
| PC-25179 |
475A
ROCK2 inhibitor
|
475A is a potent, highly selective ROCK2 inhibitor with IC50 of 1.3 nM, 162-fold selective over ROCK1 (IC50=211 nM). |
| PC-24391 |
GSK269962A
ROCK inhibitor
|
GSK269962A is a potent, selective Rho kinase (ROCK) inhibitor with IC50 of 1.6 nM (recombinant human ROCK1), 30-fold selectivity against a panel of serine/threonine kinases. |
| PC-22511 |
GNS-3595
ROCK2 inhibitor
|
GNS-3595 is a potent and selective ROCK2 inhibitor with IC50 of 5.7 nM, 80-fold selectivity over ROCK1 at 1mM ATP. |
| PC-21755 |
C3TD879
Citron kinase inhibitor
|
C3TD879 is a potent, selective first-in-class Citron kinase (CITK) chemical inhibitor with biochemical IC50 of 12 nM. |
| PC-21300 |
ITRI-E-(S)4046
ROCK/MYLK4 inhibitor
|
ITRI-E-(S)4046 (E(S)4046) is a potent, highly specific, dual synergistic inhibitor of myosin light chain kinase 4 (MYLK4) and Rho-related protein kinase (ROCK) with IC50 of 3.2 nM and 25.6 nM for ROCK1 and MYLK4, respectively. |