| Cat. No. |
Product Name |
Information |
| PC-23887 |
Hakin-1
Hakai inhibitor
|
Hakin-1 (Hakai inhibitor-1) is a specific small molecule inhibitor of the E3 ubiquitin-ligase Hakai, reduces Hakai-mediated total ubiquitination and Hakai-mediated ubiquitination of E-cadherin. |
| PC-23661 |
Y043-4427
DTX2 inhibitor
|
Y043-4427 (mDTX2i, C22H24N4O2) is a potent small molecule inhibitor of Deltex E3 ubiquitin ligase 2 (DTX2) with IC50 of 30.83 uM in Hepa1-6 cells. |
| PC-22789 |
BC-1293
FBXO24 inhibitor
|
BC-1293 is a specific small molecule inhibitor of bacterial-induced ubiquitin E3 ligase subunit FBXO24, abrogates FBXO24-DARS2 binding, exhibits immunostimulatory properties. |
| PC-22418 |
PFI-E3H1
GID4 inhibitor
|
PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction. |
| PC-22417 |
PFI-7
GID4 inhibitor
|
PFI-7 is a potent, selective and cell-active chemical probe inhibitor for GID4, a substrate-binding receptor within the C-terminal to LisH (CTLH) E3 ligase complex. |
| PC-22133 |
LS-102
Synoviolin inhibitor
|
LS-102 is a selective small molecule inhibitor of E3 ubiquitin ligase Synoviolin (SYVN1), inhibits the autoubiquitination of synoviolin with IC50 of 35 uM. |
| PC-21307 |
Smurf1 inhibitor 1
SMURF1 inhibitor
|
Smurf1 inhibitor 1 is a potent, selective Smurf1 E3 ligase inhibitor with IC50 of 230 nM in in UbFluor assays, inhibits the catalytic HECT domain of Smurf1. |
| PC-20919 |
SMURF1 inhibitor 29
SMURF1 inhibitor
|
SMURF1 inhibitor 29 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 11 nM, displays no activity against SMURF2. |
| PC-20904 |
SMURF1 inhibitor 38
SMURF1 inhibitor
|
SMURF1 inhibitor 38 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 92 nM, displays no activity against SMURF2. |
