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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-E3 Ubiquitin Ligase-N-aryl benzimidazole
N-aryl benzimidazole

Chemical Structure : N-aryl benzimidazole

CAS No.: 422554-26-5

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N-aryl benzimidazole (NAB)

货号: PC-62315Not For Human Use, Lab Use Only.

N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.

    物理化学性质&存储条件

    分子量 375.856
    分子式 C22H18ClN3O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-chlorobenzyl)-1-(m-tolyl)-1H-benzo[d]imidazole-5-carboxamide

    参考文献

    1. Tardiff DF, et al. Science. 2013 Nov 22;342(6161):979-83.

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