欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Tyrosine Kinase-VEGFR

Request The Product List ofVEGFR VEGFR

Cat. No. Product Name Information
PC-21310

NRP1-4

VEGF-A/NRP1 inhibitor

NRP1-4 (Neuropilin 1-4) is a highly potent, specific small molecule inhibitor of VEGF-A binding to neuropilin 1 (NRP1) with IC50 of 0.598 nM, reduces calcium and sodium currents through binding to NRP1 and inhibits the effects of VEGF-A.
PC-20705

COB223

Angiogenesis inhibitor

COB223 is a chemical inhibitor of angiogenesis and tumorigenesis, targets the VEGF signaling pathway upstream of Ras, inhibits endothelial cell migration with IC50 of 5 uM.
PC-73181

SAR131675

VEGFR3 inhibitor

SAR131675 is a potent and selective VEGFR3 inhibitor with IC50 of 23 nM.
PC-42859

Cabozantinib (S-malate)

Cabozantinib (XL184) is a potent, multi-kinase inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50 of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
PC-42531

Regorafenib monohydrate

A potent multikinase inhibitor that potently inhibits these endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM).
PC-42497

Vandetanib trifluoroacetate

A potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM.
PC-43353

Cediranib maleate

A highly potent, orally bioavailable, pan-VEGFR inibitor with IC50 of 1, 5, 3 nM for VEGFR1, 2, 3, respectively.

Request The Product List

  • *分类名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *国籍:
  • 留言信息:

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com