SU14813 maleate |CAS:849643-15-8 Probechem Biochemicals

Chemical Structure : SU14813 maleate

CAS No.: 849643-15-8

加入收藏

SU14813 maleate (SU-14813 maleate)

货号: PC-42623Not For Human Use, Lab Use Only.

SU14813 maleate is a broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SU14813 maleate is a broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS.
SU14813 shows poor activity for EGFR and c-Met in biochemical assays.
SU14813 inhibits VEGFR-2, PDGFR-β, and KIT phosphorylation in porcine aorta endothelial cells with IC50 of 5.2, 9.9, and 11.2 nM respectively.
SU14813 is active in xenograft tumor models.

物理化学性质&存储条件

分子量	558.5554
分子式	C27H31FN4O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrrole-3-carboxamide, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-, (2Z)-2-butenedioate (1:1)

参考文献

1. Patyna S, et al. Mol Cancer Ther. 2006 Jul;5(7):1774-82.

2. Hu-Lowe D, et al. Mol Cancer Ther. 2011 Nov;10(11):2015.

SU14813 maleate (SU-14813 maleate)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SU14813 maleate (SU-14813 maleate)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.