Tie2 inhibitor compound 5 | Tie2 inhibitor | Probechem Biochemicals

Chemical Structure : Tie2 inhibitor compound 5

CAS No.: 948557-43-5

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Tie2 inhibitor compound 5 (Tie2-IN-1)

货号: PC-24617Not For Human Use, Lab Use Only.

Tie2 inhibitor compound 5 (Tie2-IN-1) is a potent, selective Tie2 kinase inhibitor with IC50 of 250 nM, >200-fold selective over p38.

规格	价格	库存
2 mg	￥780	In stock
5 mg	￥1180	In stock
10 mg	￥1880	In stock
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

Tie2 inhibitor compound 5 (Tie2-IN-1) is a potent, selective Tie2 kinase inhibitor with IC50 of 250 nM, >200-fold selective over p38.
Tie2 inhibitor compound 5 showed efficacy in an in vivo model of angiogenesis and a MOPC-315 plasmacytoma xenograft model.

物理化学性质&存储条件

分子量	439.53
分子式	C26H21N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-(6-Methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine

参考文献

1. Marcus Semones, et al. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4756-60.

Tie2 inhibitor compound 5 (Tie2-IN-1)

生物&药学活性

物理化学性质&存储条件

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Tie2 inhibitor compound 5 (Tie2-IN-1)

生物&药学活性

物理化学性质&存储条件

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