MAZ51

Chemical Structure : MAZ51

CAS No.: 163655-37-6

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货号: PC-23424Not For Human Use, Lab Use Only.

MAZ51 is a specific inhibitor of VEGFR-3, blocks the ligand-induced autophosphorylation of VEGFR-3 and inhibits the proliferation of VEGFR-3-expressing cancer cells.

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5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

MAZ51 is a specific inhibitor of VEGFR-3, blocks the ligand-induced autophosphorylation of VEGFR-3 and inhibits the proliferation of VEGFR-3-expressing cancer cells.
MAZ51 also inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines.
MAZ51 blocks the activity of tyrosine kinases in addition to VEGFR-3.
MAZ51 significantly inhibits the growth of rat mammary carcinomas.

物理化学性质&存储条件

分子量	314.38
分子式	C21H18N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((4-(Dimethylamino)naphthalen-1-yl)methylene)indolin-2-one

参考文献

1. Kirkin V, et al. Int J Cancer. 2004 Dec 20;112(6):986-93.

2. Ny A, et al. Blood. 2008 Sep 1;112(5):1740-9.

MAZ51

生物&药学活性

物理化学性质&存储条件

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MAZ51

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