| Cat. No. |
Product Name |
Information |
| PC-42557 |
Semaxinib
VEGFR2 inhibitor
|
Semaxinib (SU5416) is a potent and specific VEGFR2 (KDR/Flk-1) inhibitor with IC50 of 1.04 uM. |
| PC-42498 |
Vandetanib hydrochloride
VEGFR2 inhibitor
|
Vandetanib hydrochloride is a potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
| PC-42496 |
Vandetanib
VEGFR2 inhibitor
|
Vandetanib (ZD6474) is a potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
| PC-45746 |
Fruquintinib
VEGFR inhibitor
|
Fruquintinib (HMPL-013) is a potent and highly selective small molecule inhibitor of VEGFR1/2/3 with IC50 of 33/3/5/0.5 nM, respectively. |
| PC-42762 |
Lenvatinib
VEGFR inhibitor
|
Lenvatinib (E7080) is a multitargeted kinase inhibitor with IC50s of 4/5.2/22/46 nM for VEGFR2/VEGFR3/VEGFR1/FGFR1 in cell free assays. |
| PC-43353 |
Cediranib maleate
VEGFR inhibitor
|
Cediranib maleate (AZD2171) is a highly potent, orally bioavailable, pan-VEGFR inibitor with IC50 of 1, 5, 3 nM for VEGFR1, 2, 3, respectively. |
| PC-42450 |
Cediranib
VEGFR inhibitor
|
Cediranib (AZD2171) is a highly potent, orally bioavailable, pan-VEGFR inibitor with IC50 of 1, 5, 3 nM for VEGFR1, 2, 3, respectively. |
| PC-42759 |
Tivozanib
VEGFR inhibitor
|
Tivozanib (AV951) is a highly potent inhibitor of pan-VEGFR with IC50s of 60/6.5/15 nM for VEGFR1/2/3. |
| PC-42534 |
Brivanib (BMS540215)
VEGFR2/FGFR1 inhibitor
|
Brivanib (BMS540215) is a potent, dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively. |
| PC-42623 |
SU14813 maleate
Multikinase inhibitor
|
SU14813 maleate is a broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS. |
| PC-42622 |
SU14813
Multikinase inhibitor
|
SU14813 is a potent, broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS. |
| PC-25873 |
Amentoflavone
VEGFR phosphorylation inhibitor
|
Amentoflavone is a naturally occurring biflavonoid with anti-inflammatory and anti-tumor properties, an antiangiogenic bioactive molecule that binds VEGFs preventing the interaction and phosphorylation of VEGF receptor 1 and 2 (VEGFR-1,VEGFR-2). |
