| Cat. No. |
Product Name |
Information |
| PC-47022 |
P7C3
NAMPT activator
|
P7C3 is an aminopropyl carbazole having proneurogenic and neuroprotective properties, protects newborn neurons from apoptotic cell death, binds to and activates nicotinamide phosphoribosyltransferase (NAMPT). |
| PC-38787 |
GNE-618
NAMPT inhibitor
|
GNE-618 is a potent, selective NAMPT inhibitor with IC50 of 6 nM, depletes NAD and induces cell death in vitro and in vivo. |
| PC-38786 |
GNE-617
NAMPT inhibitor
|
GNE-617 is a potent, selective, cellularly active NAMPT inhibitor with IC50 of 5 nM, inhibits multiple cancer cell lines (U251, HT1080, PC3, MiaPaCa2, and HCT116 lines) with IC50 of <10 nM. |
| PC-38440 |
NAMPT activator (NAT-5r)
NAMPT activator
|
NAMPT activator (NAT-5r) is a potent, small molecule activator of nicotinamide phosphoribosyltransferase (NAMPT) with ITC KD of 180 nM, 3-fold improved activity over NAT. |
| PC-38439 |
NAMPT activator (NAT)
NAMPT activator
|
NAMPT activator (NAT) is a potent, small molecule activator of nicotinamide phosphoribosyltransferase (NAMPT) with ITC KD of 500 nM. |
| PC-73040 |
GNI-50
NAMPT inhibitor
|
GNI-50 is a potent, selective Nampt inhibitor with enzyme IC50 of 7 nM, A2780 cellular IC50 of 32 nM. |
| PC-73039 |
SBI-797812
NAMPT activator
|
SBI-797812 (SBI 797812) is a specific small molecule NAMPT activator with EC50 of 0.37 uM, increases NAMPT-catalyzed NMN synthesis by 2.1-fold (Emax). |
| PC-38153 |
OT-82
NAMPT inhibitor
|
OT-82 (NAMPT inhibitor OT-82) is a novel selective and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), reduces the viability of leukemia cells with IC50 of 0.2-4 nM. |
| PC-43221 |
STF-118804
NAMPT inhibitor
|
STF-118804 is a potent, highly specific NAMPT inhibitor, reduces the viability of most B-ALL cell lines with high potency in the low nanomolar range (MV411 cell IC50= 6 nM). |
| PC-61000 |
AS1604498
NAMPT inhibitor
|
AS1604498 is a potent nicotinamide phosphoribosyl transferase (NAMPT) inhibitor with IC50 of 44 nM. |
| PC-60773 |
LSN 3154567
NAMPT inhibitor
|
LSN3154567 is a novel potent, highly selective, competitive NAMPT inhibitor with IC50 of 3.1 nM. |
| PC-60007 |
GMX-1777 chloride
NAMPT inhibitor
|
GMX-1777 chloride (Teglarinad) is the water-soluble prodrug of GMX-1778 (CHS-828), which is a potent and specific inhibitor of the NAD(+) biosynthesis enzyme NAMPT with IC50 of <20 nM. |
