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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-NAMPT-P7C3
P7C3

Chemical Structure : P7C3

CAS No.: 301353-96-8

P7C3 (NAMPT activator P7C3)

货号: PC-47022Not For Human Use, Lab Use Only.

P7C3 is an aminopropyl carbazole having proneurogenic and neuroprotective properties, protects newborn neurons from apoptotic cell death, binds to and activates nicotinamide phosphoribosyltransferase (NAMPT).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

P7C3 is an aminopropyl carbazole having proneurogenic and neuroprotective properties, protects newborn neurons from apoptotic cell death, binds to and activates nicotinamide phosphoribosyltransferase (NAMPT).

物理化学性质&存储条件

分子量 474.196
分子式 C21H18Br2N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,6-Dibromo-alpha-[(phenylamino)methyl]-9H-carbazole-9-ethanol

参考文献

1. Pieper AA, et al. Cell. 2010 Jul 9;142(1):39-51.

2. Wang G, et al. Cell. 2014 Sep 11;158(6):1324-1334.

3. MacMillan KS, et al. J Am Chem Soc. 2011 Feb 9;133(5):1428-37.

4. Tesla R, et al. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17016-21.

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