NAMPT activator (NAT) | NAMPT activator | Probechem Biochemicals

Chemical Structure : NAMPT activator (NAT)

CAS No.: 831243-31-3

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NAMPT activator (NAT) (NAMPT activator NAT)

货号: PC-38439Not For Human Use, Lab Use Only.

NAMPT activator (NAT) is a potent, small molecule activator of nicotinamide phosphoribosyltransferase (NAMPT) with ITC KD of 500 nM.

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10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
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生物&药学活性

NAMPT activator (NAT) is a potent, small molecule activator of nicotinamide phosphoribosyltransferase (NAMPT) with ITC KD of 500 nM.
NAMPT activator (NAT) markedly increased the catalytic activity (Vmax) of NAMPT with higher Michaelis constants (Km) for both substrates, NAM, and PRPP.
The stoichiometry analysis revealed that NAT bound to NAMPT at a 1:1 ratio, NAT may function as a reversible activator during the kinetic assay, and has no effect on NMNAT1 enzyme activity.

物理化学性质&存储条件

分子量	299.370
分子式	C18H21NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(tert-butyl)phenoxy)-N-(4-hydroxyphenyl)acetamide

参考文献

1. Hong Yao, et al. Cell Research (2022) 0:1-15.

NAMPT activator (NAT) (NAMPT activator NAT)

生物&药学活性

物理化学性质&存储条件

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NAMPT activator (NAT) (NAMPT activator NAT)

生物&药学活性

物理化学性质&存储条件

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