| Cat. No. |
Product Name |
Information |
| PC-20347 |
TJ-M2010-2
MyD88 inhibitor
|
TJ-M2010-2 is a small molecule inhibitor of MyD88 homodimerization, interacts with MyD88 TIR domain. |
| PC-38670 |
TJ-M2010-5
MyD88 inhibitor
|
TJ-M2010-5 is a small molecule MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway. |
| PC-72669 |
Compound 4210
MyD88 inhibitor
|
Compound 4210 (MyD88 inhibitor 4210) is a small molecule inhibitor of MyD88, inhibits LPS-induced MyD88-mediated NF-kB-dependent expression of reporter activity with IC50 of 10-30 uM. |
| PC-35815 |
T5910047
MyD88 inhibitor
|
T5910047 (T-5910047) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation. |
| PC-35814 |
T6167923
MyD88 inhibitor
|
T6167923 (T-6167923) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation. |
| PC-45910 |
ST2825
MyD88 inhibitor
|
ST-2825 (ST2825) is a synthetic peptido-mimetic compound that inhibits MyD88 dimerization in a TIR-dependent manner. |
| PC-23609 |
T5996207
MyD88 inhibitor
|
T5996207 is a specific small molecule inhibitors of MyD88-dependent signaling pathway, inhibits LPS induced MyD88-mediated NF-kB driven SEAP expression with IC50 of 40-50 uM. |
| PC-23608 |
MyD88 inhibitor A5S
MyD88 inhibitor
|
MyD88 inhibitor A5S is a specific small molecule MyD88 inhibitor with SPR Kd of 15 uM, exerts anti-inflammatory effect through the NF-κB/MAPK pathway. |
| PC-23573 |
Lasalocid sodium
MYD88 L265P degrader
|
Lasalocid sodium (Lasalocid A, Lasalocid-A) is a feed additive widely used in ruminant nutrition, selectively induces the degradation of MYD88 in lymphomas harboring the MYD88 L265P mutation, directly binds to the MYD88 L265P protein, enhancing its interaction with the E3 ligase RNF5. |
| PC-23572 |
Lasalocid
MYD88 L265P degrader
|
Lasalocid (Lasalocid A, Lasalocid-A) is a feed additive widely used in ruminant nutrition, selectively induces the degradation of MYD88 in lymphomas harboring the MYD88 L265P mutation, directly binds to the MYD88 L265P protein, enhancing its interaction with the E3 ligase RNF5. |
| PC-21179 |
MyD88 inhibitor 15d
MyD88 inhibitor
|
MyD88 inhibitor 15d is a potent, small molecule inhibitor of MyD88 homodimerization, dose-dependently inhibits LPS-induced IL-6 and TNF-α in macrophages with IC50 of 2.52 and 0.89 uM, respectively. |
| PC-21177 |
MyD88 inhibitor C17
MyD88 inhibitor
|
MyD88 inhibitor C17 is a highly potent inhibitor of myeloid differentiation primary response protein 88 (MyD88), dose-dependently inhibits LPS-induced IL-6 and TNF-α in J774A.1 macrophages with IC50 of 2.17 and 8.17 uM, respectively. |
