| Cat. No. |
Product Name |
Information |
| PC-60265 |
T-3775440 hydrochloride
LSD1 inhibitor
|
T-3775440 hydrochloride (T 3775440, T3775440) is a potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM. |
| PC-60264 |
T-3775440
LSD1 inhibitor
|
T-3775440 (T 3775440, T3775440) is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM. |
| PC-60020 |
KDOAM-25
KDM5 inhibitor
|
KDOAM-25 (KDM5 inhibitor KDOAM 25) is a potent, selective KDM5 sub-family(JARID1) inhibitor with biochemical IC50 of 71/19/69/69 nM for KDM5A/B/C/D, respectively. |
| PC-45657 |
DDP-38003 dihydrochloride
LSD1 inhibitor
|
DDP-38003 dihydrochloride is a potent, selective and orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with IC50 of 84 nM. |
| PC-42028 |
KDM5A-IN-1
KDM5 inhibitor
|
KDM5A-IN-1 is a potent, orally bioavailable histone lysine demethylases 5 (KDM5) inhibitor with IC50 of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively. |
| PC-42148 |
CPI-455
KDM5 inhibitor
|
CPI-455 is a potent, specific histone demethylase pan-KDM5 inhibitor with biochemical IC50 of 10, 3 and 14 nM for KDM5A, KDM5B and KDM5C, respectively. |
| PC-45495 |
GSK2879552
LSD1 inhibitor
|
GSK2879552 is a potent, selective irreversible inhibitor of LSD1 with Ki app of 1.7 uM. |
| PC-42149 |
KDM5-IN-48
KDM5 inhibitor
|
KDM5-IN-48 is a potent, selective and orally bioavailable KDM5 inhibitor with biochemical IC50 of 15.1, 4.7 and 65.5 nM for KDM5A, KDM5B and KDM5C, respectively. |
| PC-42195 |
D-alpha-Hydroxyglutaric acid disodium
Dioxygenase inhibitor
|
D-alpha-Hydroxyglutaric acid disodium (D-2-HG, D-2-hydroxyglutarate) is a competitive inhibitor of multiple α-KG-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases. |
| PC-25582 |
Methylstat
JHDMs inhibitor
|
Methylstat is a selective inhibitor of Jumonji C domain-containing histone demethylases (JHDMs) in cells, preferentially inhibits JMJD2A (H3K9me3 and H3K36me3 demethylase), JMJD2E (H3K9me3 demethylase) and JMJD3 (H3K27me3 demethylase). |
| PC-24718 |
Tranylcypromine hydrochloride
LSD1 inhibitor
|
Tranylcypromine (SKF385) hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1, KDM1A) and monoamine oxidase (MAO), inhibits LSD1, MAO-A and MAO-B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. |
| PC-24469 |
FTO inhibitor F97
FTO inhibitor
|
F97 is a specific small molecule inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 0.45 uM, selectively inhibits m6A demethylation by FTO rather than ALKBH5, and has minimal effect on m1A demethylation by ALKBH3. |
