| Cat. No. |
Product Name |
Information |
| PC-22360 |
KDM4/5 inhibitor 19a
KDM4/5 inhibitor
|
KDM4/5 inhibitor 19a is a potent, cell penetrant, dual KDM4/5-subfamily inhibitor with Ki values of 4 nM/7 nM for KDM4A/KDM5B, respectively. |
| PC-22359 |
N19-0881
KDM5B inhibitor
|
KDM5-N19 (N19-0881) is a potent, selective, αKG-competitive KDM5B inhibitor with IC50 of 2 nM. |
| PC-22357 |
2,4-PDCA
2OG oxygenase inhibitor
|
2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenases, including JmjC domain-containing family of histone demethylases (JHDMs), shows acceptable KDM5B inhibition in vitro, with an IC50 value of 3 uM. |
| PC-21988 |
KDOAM-25 citrate
KDM5 inhibitor
|
KDOAM-25 citrate (KDM5 inhibitor KDOAM 25) is a potent, selective KDM5 sub-family (JARID1) inhibitor with biochemical IC50 of 71/19/69/69 nM for KDM5A/B/C/D, respectively. |
| PC-21875 |
WS-384
LSD1 inhibitor
|
WS-384 is a specific, small-molecule inhibitor dually targeting LSD1 (IC50=338.8 nM) and the DCN1-UBC12 interaction (IC50=14.8 uM). |
| PC-21777 |
JMJD1C inhibitor 193D7
JMJD1C inhibitor
|
193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells. |
| PC-20876 |
ZY0511
LSD1 inhibitor
|
ZY0511 is a highly selective and potent inhibitor of lysine‐specific histone demethylase 1 (LSD1) with IC50 of 1.7 nM and SPR Kd of 2.42 nM. |
| PC-20519 |
TAK-418
LSD1 (KDM1A) inhibitor
|
TAK-418 (TAK418) is a potent, specific inhibitor of LSD1 (KDM1A) enzyme activity with IC50 of 2.9 nM. |
