| Cat. No. |
Product Name |
Information |
| PC-24002 |
LH-1802
LSD1 inhibitor
|
LH1802 is a potent, selective and reversible inhibitor of lysine-specific demethylase 1 (LSD1) with EC50 of 470 nM (CD86). |
| PC-24001 |
CBB1007 trihydrochloride
LSD1 inhibitor
|
CBB1007 trihydrochloride is a cell-permeable, potent, reversible and substrate competitive (LSD1, KDM1A) selective inhibitor with IC50 of 5.27 uM. |
| PC-24000 |
CBB1007
LSD1 inhibitor
|
CBB1007 is a cell-permeable, potent, reversible and substrate competitive LSD1 selective inhibitor with IC50 of 5.27 uM. |
| PC-23999 |
CBB1003
LSD1 inhibitor
|
CBB1003 is a novel lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 10.54 uM. |
| PC-23897 |
FTO inhibitor Dac85
FTO inhibitor
|
FTO inhibitor Dac85 is a small molecule inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 0.7 uM, displays strong antiproliferative effect on AML cells. |
| PC-23879 |
N-CDPCB
FTO inhibitor
|
N-CDPCB is a small molecule inhibitor of fat mass and obesity associated protein (FTO), displays strong inhibitory activity of demethylation of the ssRNA by FTO with IC50 of 4.95 uM. |
| PC-23878 |
FTO inhibitor 8t
FTO inhibitor
|
FTO inhibitor 8t is a novel specific small molecule inhibitor of RNA demethylase FTO with IC50 of 7.3 uM. |
| PC-23678 |
DDO-02267
ALKBH5 inhibitor
|
DDO-02267 is a potent, specific, lysine-targeting covalent inhibitor of ALKBH5 with binding KD of 2.8 uM in ITC assay and IC50 of 174.7 nM in FP assay, specifically targets lysine 132 (Lys132). |
| PC-23677 |
ALKBH5 inhibitor Ena21
ALKBH5 inhibitor
|
Ena21 is a selective small molecule m6A demethylation enzyme ALKBH5 inhibitor with IC50 of 15.7 uM, shows little activity for FTO. |
| PC-23676 |
ALKBH5 inhibitor Ena15
ALKBH5 inhibitor
|
Ena15 is a selective small molecule m6A demethylation enzyme ALKBH5 inhibitor with IC50 of 18.3 uM, also enhances the demethylase activity of FTO. |
| PC-23648 |
ZLD115
FTO inhibitor
|
ZLD115 is a potent, selective inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 2.3 uM in PAGE-based assays. |
| PC-23548 |
Rhein
ALKBH inhibitor
|
Rhein is a pan inhibitor of the ALKBH proteins, inhibits ALKBH2, ALKBH3 and FTO with IC50 values of 9.1 μM, 5.3 μM and 21.0 μM, respectively. |
