N-CDPCB

Chemical Structure : N-CDPCB

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货号: PC-23879Not For Human Use, Lab Use Only.

N-CDPCB is a small molecule inhibitor of fat mass and obesity associated protein (FTO), displays strong inhibitory activity of demethylation of the ssRNA by FTO with IC50 of 4.95 uM.

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生物&药学活性

N-CDPCB is a small molecule inhibitor of fat mass and obesity associated protein (FTO), displays strong inhibitory activity of demethylation of the ssRNA by FTO with IC50 of 4.95 uM.
N-CDPCB (10 uM) inhibits FTO-mediated m6A modification of mRNA in preadipocytes (3T3-L1 cells).
N-CDPCB enhances m6A of mRNA of preadipocytes.

物理化学性质&存储条件

分子量	317.77
分子式	C17H16ClNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-Chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutanecarboxamide

参考文献

1. He W, et al. J Med Chem. 2015 Sep 24;58(18):7341-8.

N-CDPCB

生物&药学活性

物理化学性质&存储条件

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N-CDPCB

生物&药学活性

物理化学性质&存储条件

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