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首页-小分子抑制剂&激动剂-Epigenetics-Histone Demethylase-OG-L002
OG-L002

Chemical Structure : OG-L002

CAS No.: 1357302-64-7

OG-L002 (OG L002)

货号: PC-61746Not For Human Use, Lab Use Only.

OG-L002 is a novel selective LSD1 inhibitor with IC50 of 20 nM.

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10 mg ¥1180 In stock
25 mg ¥1880 In stock
50 mg ¥2980 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

OG-L002 is a potent, selective LSD1 inhibitor with IC50 of 20 nM.
OG-L002 demonstrates significant potency both in inhibition of HSV IE gene expression and in suppression of viral reactivation from latency in a mouse ganglion explant model.
OG-L002 also suppresses the expression of the initial class of hCMV and adenovirus genes in vitro.
OG-L002 reduces the induction of TNF-α mRNA in splenocytes from mice.

物理化学性质&存储条件

分子量 225.3
分子式 C15H15NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4'-[(1R,2S)-2-aminocyclopropyl]-[1,1'-biphenyl]-3-ol

参考文献

1. Seifermann M, et al. DNA Repair (Amst). 2017 Oct;58:13-20.

2. Liang Y, et al. MBio. 2013 Feb 5;4(1):e00558-12.

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