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SD-70

Chemical Structure : SD-70

CAS No.: 332173-89-4

SD-70 (SD70, KDM4C inhibitor)

货号: PC-70332Not For Human Use, Lab Use Only.

SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).

规格 价格 库存 数量
2 mg ¥1980 In stock
5 mg ¥3280 In stock
10 mg ¥5280 In stock
25 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: 98.1% (HPLC) Select Batch:

生物&药学活性

SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).
SD-70represses AR transcriptional program, increases H3K9me2 levels in 293T cells.
SD-70 inhibits tumor growth in CWR22Rv1 prostate cancer xenograft mice model.

物理化学性质&存储条件

分子量 310.353
分子式 C18H18N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(furan-2-yl(8-hydroxyquinolin-7-yl)methyl)isobutyramide

参考文献

1. Jin C, et al. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9235-40.

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