| Cat. No. |
Product Name |
Information |
| PC-35223 |
Clobenpropit dihydrobromide
Histamine H3 inverse agonist
|
Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors. |
| PC-35222 |
Clobenpropit
Histamine H3 antagonist
|
Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors. |
| PC-63422 |
UR-PI376
Histamine H4 agonist
|
UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R.. |
| PC-63421 |
OUP-16
Histamine H4 agonist
|
OUP-16 is a potent H4R agonist with a considerable selectivity over H3R. |
| PC-63420 |
A-943931
Histamine H4 antagonist
|
A-943931 is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively. |
| PC-63419 |
A-943931 dihydrochloride
Histamine H4 antagonist
|
A-943931 dihydrochloride is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively. |
| PC-63418 |
VUF 10214
Histamine H4 ligand
|
VUF-10214 is a potent, selective histamine H4 receptor (H4R) ligand with pKi of 7.4, shows anti-inflammatory properties in vitro. |
| PC-63417 |
JNJ-40279486
Histamine H4 antagonist
|
JNJ-40279486 is a potent, selective histamine H4 receptor antagonist with Ki of 9.4 nM (hH4), demonstrates acceptable pharmacokinetic profile and efficacy in mouse model of inflammation.. |
| PC-63413 |
JNJ-28610244
Histamine H4 agonist
|
JNJ-28610244 is a potent, selective agonist of histamine H4 receptor (H4R) with pKi of 7.3 and pEC50 of 7.0 respectively, |
| PC-63410 |
JNJ-28307474
Histamine H4 antagonist
|
JNJ-28307474 is a potent, selective antagonist of the histamine H4 receptor (H4R), inhibits LPS-induced TNF production. |
| PC-63399 |
Toreforant
Histamine H4 antagonist
|
Toreforant (JNJ-38518168) is a potent, selective histamine H4 receptor (H4R) antagonist with Ki of 8.4 nM, shows excellent selectivity over other receptors including the other histamine receptors. |
| PC-63035 |
MK-0249
Histamine H3 antagonist
|
MK-0249 is a potent, selective and orally active histamine H3 receptor antagonist, with an IC50 of 1.7 nM for human H3. |
