JNJ-40279486 |CAS:1002351-34-9 Probechem Biochemicals

Chemical Structure : JNJ-40279486

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JNJ-40279486 (JNJ40279486)

货号: PC-63417Not For Human Use, Lab Use Only.

JNJ-40279486 is a potent, selective histamine H4 receptor antagonist with Ki of 9.4 nM (hH4), demonstrates acceptable pharmacokinetic profile and efficacy in mouse model of inflammation..

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JNJ-40279486 is a potent, selective histamine H4 receptor antagonist with Ki of 9.4 nM (hH4), demonstrates acceptable pharmacokinetic profile and efficacy in mouse model of inflammation.

物理化学性质&存储条件

分子量	318.765
分子式	C14H15ClN6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-8-chloro-4-(3-(methylamino)pyrrolidin-1-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-amine

参考文献

1. Savall BM, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6577-81.

JNJ-40279486 (JNJ40279486)

生物&药学活性

物理化学性质&存储条件

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JNJ-40279486 (JNJ40279486)

生物&药学活性

物理化学性质&存储条件

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