UR-PI376 |CAS:1192559-94-6 Probechem Biochemicals

Chemical Structure : UR-PI376

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UR-PI376 (UR PI376)

货号: PC-63422Not For Human Use, Lab Use Only.

UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R..

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生物&药学活性

UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R.

物理化学性质&存储条件

分子量	342.465
分子式	C17H22N6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-cyano-1-[4-(1H-imidazol-4-yl)butyl]-3-[(2-phenylthio)ethyl]guanidine

参考文献

1. Igel P, et al. J Med Chem. 2009 Oct 22;52(20):6297-313.

2. Reher TM, et al. Biochem Pharmacol. 2012 Jul 15;84(2):192-203.

3. Gschwandtner M, et al. Br J Pharmacol. 2013 Sep;170(1):136-43.

UR-PI376 (UR PI376)

生物&药学活性

物理化学性质&存储条件

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UR-PI376 (UR PI376)

生物&药学活性

物理化学性质&存储条件

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