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首页-小分子抑制剂&激动剂-GPCR-Histamine Receptor

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Cat. No. Product Name Information
PC-23473

JNJ-7777120

H4R antagonist

JNJ-7777120 (JNJ 7777120) is potent and selective histamine H4 receptor (H4R) antagonist with Ki of 4.5 nM (hH4R), >1000-fold selectivity over H1, H2, or H3 receptors.
PC-23262

Izuforant

H4R antagonist

Izuforant (JW1601, LEO 152020) is a potent, selective and oral histamine 4 receptor (H4R) antagonist with IC50 of 65.1-72.2 nM in human whole-blood assay, and pKi of 6.83 and 5.36 at mouse and rat histamine receptor subtypes. shows lower pKi values against other histamine receptor.
PC-42910

Pitolisant oxalate

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.

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