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首页-小分子抑制剂&激动剂-GPCR-Histamine Receptor-Pitolisant oxalate
Pitolisant oxalate

Chemical Structure : Pitolisant oxalate

CAS No.: 362665-57-4

Pitolisant oxalate (Tiprolisant oxalate)

货号: PC-42910Not For Human Use, Lab Use Only.

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.

规格 价格 库存 数量
50 mg ¥3584.0 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM); orally bioactive.

Sleep Disorder

Approved

物理化学性质&存储条件

分子量 385.8823
分子式 C19H28ClNO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-, ethanedioate (1:1)

参考文献

1. Ligneau X, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):365-75.

2. Dudek M, et al. Metab Brain Dis. 2016 Oct;31(5):1023-9.

3. Ligneau X, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1215-24.

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