| Cat. No. |
Product Name |
Information |
| PC-20789 |
Erg6 inhibitor H55
Fungal Erg6 inhibitor
|
Erg6 inhibitor H55 is an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase (Erg6), potently inhibits C. albicans hyphal formation in multiple cultural conditions. |
| PC-49414 |
MMV688766
Antifungal
|
MMV688766 (MMV 688766) is a small molecule displaying broad-spectrum fungicidal activity through perturbation of lipid homeostasis, inhibits the growth of four geographically distinct C. auris clades with MIC80 of 12.5-50 uM. |
| PC-38699 |
YU385599
Fungal PanK inhibitor
|
YU385599 is a potent small molecule inhibitor of fungal pantothenate kinase (PanK) with Ki of 106 nM (A. fumigatus AfPanK), also inhibits S. cerevisiae Cab1 enzyme with Ki of 170 nM, inhibits the growth of several Candida species. |
| PC-38447 |
Fluxapyroxad
Succinate dehydrogenase inhibitor
|
Fluxapyroxad is a new generation carboxamide funugicide and succinate dehydrogenase (Sdh) inhibitor, exhibits antifungal activities against R. solani with EC50 of 0.033 mg/mL. |
| PC-73393 |
1-ECBC
Yak1 inhibitor
|
1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans. |
| PC-73392 |
1-ABC
Yak1 inhibitor
|
1-ABC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans. |
| PC-72457 |
Azoffluxin
Cdr1 inhibitor
|
Azoffluxin (CMLD012336) is a bis-benzodioxolylindolinone that synergizes with fluconazole against C. auris through the inhibition of efflux pump Cdr1, thus increasing intracellular fluconazole levels. |
| PC-72423 |
GW461484A
Yck2 inhibitor
|
GW461484A (GW-461484A) is a potent small molecule capable of restoring caspofungin sensitivity, inhibits Yck2 kinase in C. albicans, originally discovered as an inhibitor of human p38α with IC50 of 150 nM. |
| PC-38031 |
Rezafungin
Antifungal
|
Rezafungin (CD101) is a long-acting novel echinocandin possesses potent antibiofilm activity against early and mature candida albicans biofilms. |
| PC-38016 |
Echinocandin B
|
Echinocandin B (ECBN) is a cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus nidulans var. echinulatus with specific anti-yeast activity. |
| PC-35452 |
Fosmanogepix
Gwt1 inhibitor
|
Fosmanogepix (APX001, E1211) is a novel antifungal agent, the prodrug form of Manogepix, which inhibits the fungal protein Gwt1. |
| PC-63228 |
ML316
Mir1 inhibitor
|
ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1, exhibits potent antifungal activity against the moderatelyazole-resistant C. albicans strain CaCi-2 with MIC of 0.05 ug/ml. |
