| Cat. No. |
Product Name |
Information |
| PC-63228 |
ML316
Mir1 inhibitor
|
ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1, exhibits potent antifungal activity against the moderatelyazole-resistant C. albicans strain CaCi-2 with MIC of 0.05 ug/ml. |
| PC-62615 |
PC945
Antifungal
|
Opelconazole (PC945) is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively. |
| PC-62607 |
PC1244
Fungal CYP51A/CYP51B inhibitor
|
PC1244 is a long acting fungicidal azole that targets A. fumigatus CYP51A and CYP51B, inhibits ergosterol synthesis in A. fumigatus with IC50 of 8 nM. |
| PC-61753 |
VT-1161
Fungal CYP51 inhibitor
|
VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM. |
| PC-61752 |
VT-1598
Fungal CYP51B inhibitor
|
VT-1598 is a potent, high-affinity, oral inhibitor of fungal sterol 14α-demethylase (CYP51B) with Kd of 13 nM. |
| PC-70346 |
Filastatin
Antifungal
|
Filastatin is a small molecule inhibitor that inhibits adhesion of C. albicans to polystyrene. |
| PC-70224 |
F-901318
Fungal DHODH inhibitor
|
F-901318 (Olorofim) is a novel antifungal agent that inhibits A. fumigatus DHODH with IC50 of 44 nM. |
| PC-60335 |
iKIX1
Antifungal
|
iKIX1 is a small-molecule inhibitor of the interaction of the C. glabrata Pdr1 activation domain with the C. glabrata Gal11A KIX domain with Ki of 18 uM. |
| PC-60051 |
Quilseconazole
Fungal CYP51 inhibitor
|
A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor. |
| PC-45366 |
Micafungin sodium
Antifungal
|
Micafungin sodium (FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase, inhibits the production of 1,3-β-D-glucan in fungal cell walls, acts as a neddylation inhibitor that targets Ubiquitin-conjugating enzyme 2M (UBE2M). |
| PC-42761 |
AN-2690
LeuRS inhibitor
|
AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis. |
| PC-42727 |
Clotrimazole
Antifungal, UGT2B4 inhibitor
|
Clotrimazole is an antifungal agent that works by altering the permeability of the fungal cell wall, also is a selective inhibitor of UGT2B4. |
