欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-MBX-7591
MBX-7591

Chemical Structure : MBX-7591

CAS No.: 2096324-50-2

加入收藏

MBX-7591 (MBX7591)

货号: PC-22712Not For Human Use, Lab Use Only.

MBX-7591 is a nonspirocyclic piperidine antifungal agent with MIC of 1.2 uM for A. fumigatus, shows promising antifungal activity against Aspergillus fumigatus and other pathogenic fungi, including strains resistant to triazoles.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MBX-7591 is a nonspirocyclic piperidine antifungal agent with MIC of 1.2 uM for A. fumigatus, shows promising antifungal activity against Aspergillus fumigatus and other pathogenic fungi, including strains resistant to triazoles.
MBX-7591 exhibits synergy with triazole antifungal drugs and activity against pan-azole-resistant A. fumigatus isolates.
MBX-7591 has additional potent activity against Rhizopus species and CO2-dependent activity against Cryptococcus neoformans. 
MBX-7591 increases cell membrane saturation by decreasing oleic acid content.
MBX-7591 has low toxicity in vivo and shows good efficacy in decreasing fungal burden in a murine model of invasive pulmonary aspergillosis.

物理化学性质&存储条件

分子量 392.52
分子式 C23H24N2O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4-(4-((pyridin-4-yloxy)methyl)benzyl)piperidin-1-yl)(thiophen-3-yl)methanone

参考文献

1. Gutierrez-Perez C, et al. mBio. 2024 Jul 17;15(7):e0116624.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: