| Cat. No. |
Product Name |
Information |
| PC-42167 |
TBID
HIPK2 inhibitor
|
tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM. |
| PC-25353 |
DYRK1A/1B inhibitor 8h
DYRK1A/DYRK1B inhibitor
|
DYRK1A/1B inhibitor 8h is a potent, selective DYRK1A/DYRK1B inhibitor with IC50 of 5 nM and 3 nM respectively. |
| PC-25352 |
KS-40070
DYRK1B inhibitor
|
KS-40070 is a potent, selective inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1B (DYRK1B) with IC50 of 18 nM, with no inhibition on human DYRK2 (IC50>10 uM). |
| PC-23759 |
SM15685
DYRK1A/B inhibitor
|
SM15685 is a highly selective and potent, oral, brain-penetrant DYRK1A/B inhibitor with IC50 of 1 nM (DYRK1A). |
| PC-23472 |
GSK626616
DYRK3 inhibitor
|
GSK626616 is a potent, orally bioavailable inhibitor of DYRK3 with IC50 of 0.7 nM, inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency. |
| PC-23353 |
NSC361563
DYRK1A inhibitor
|
NSC361563 is a potent and selective DYRK1A inhibitor with IC50 of 1.38 uM. |
| PC-23236 |
DYR530
DYRK1 inhibitor
|
DYR530 is a potent, selective inhibitor of DYRK1 with Kd of 0.91 nM (DYRK1A). |
| PC-23235 |
DYR533
DYRK1 inhibitor
|
DYR533 is a potent, selective inhibitor of DYRK1 with Kd of 1.4 nM (DYRK1A), blocks mnb phosphorylation of human Tau expressed in Drosophila neurons. |
| PC-23234 |
DYR219
DYRK1 inhibitor
|
DYR219 is a potent, selective, type 1 ATP-competitive inhibitor of DYRK1 with IC50 of 34 nM (DYRK1A) and 29 nM (DYRK1B), induces degradation of Dyrk1a protein. |
| PC-23001 |
DYRK inhibitor ID-8
DYRK inhibitor
|
DYRK inhibitor ID-8 is a small molecule dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor, enhances Wnt-induced human embryonic stem cell (hESC) survival and proliferation. |
| PC-22601 |
DYC-1
DYRK2/HDAC8 inhibitor
|
DYC-1 is a potent, dual-target DYRK2/HDAC8 inhibitor with IC50 of 5.27 and 8.06 nM respectively, exhibits potent antiproliferative and antitumor activity against liver cancer. |
| PC-22437 |
proINDY
DYRK1A inhibitor
|
proINDY is the acetylated derivative prodrug of INDY, which is a potent, selective and ATP-competitive inhibitor of Dyrk1A, effectively recovers Xenopus embryos from head malformation induced by Dyrk1A overexpression. |
