Chemical Structure : TBID
CAS No.: 1639895-85-4
货号: PC-42167Not For Human Use, Lab Use Only.
tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM.
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tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM.
tBID displays selectivity Gini coefficient 0.592 out of a panel of 76 kinases, and also inhibits HIPK1 and HIPK3 with less efficiently.
tBID the first pharmacological tool to down regulate cellular HIPK2 in cells.
分子量 | 528.7764 | |
分子式 | C11H3Br4N3O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
DMSO: 26 mg/mL |
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Chemical Name/SMILES |
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl)- |
1. Cozza G, et al. PLoS One. 2014 Feb 24;9(2):e89176.
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