JWD-065 | HIPK2 inhibitor | Probechem Biochemicals

Chemical Structure : JWD-065

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JWD-065 (JWD 065)

货号: PC-73292Not For Human Use, Lab Use Only.

JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.

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100 mg		Get quote

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生物&药学活性

JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.

物理化学性质&存储条件

分子量	462.572
分子式	C24H26N6O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propenamide, N-[3-[[4-amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl]carbonyl]phenyl]-

参考文献

1. Sebum Lee, et al. Neuron. 2016, 91(1), 41-55.

2. Miduturu CV et al. Chem Biol. 2011;18:868–879.

JWD-065 (JWD 065)

生物&药学活性

物理化学性质&存储条件

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JWD-065 (JWD 065)

生物&药学活性

物理化学性质&存储条件

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