| Cat. No. |
Product Name |
Information |
| PC-43226 |
TH-588
MTH1 inhibitor
|
TH-588 is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 5 nM. |
| PC-45105 |
TH-287 hydrochloride
MTH1 inhibitor
|
TH-287 hydrochloride is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 0.8 nM. |
| PC-45104 |
TH-287
MTH1 inhibitor
|
TH-287 is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 0.8 nM. |
| PC-24067 |
SAR-24
PCNA inhibitor
|
SAR-24 is a small molecule inhibitor of proliferating cell nuclear antigen (PCNA), significantly affects chromatin-associated PCNA in tumor cells, effectively decreasing its levels and thereby inhibiting cancer cell proliferation. |
| PC-24066 |
ATX-101
PCNA inhibitor
|
ATX-101 is an APIM-containing cell-penetrating peptide targeting PCNA, impairs the APIM-PCNA interaction. |
| PC-24057 |
KWR137
WRN inhibitor
|
KWR137 is a novel potent inhibitor of Werner protein WRN with IC50 of 8 nM (WRN ATPase). |
| PC-24056 |
KWR095
WRN inhibitor
|
KWR095 is a novel potent inhibitor of Werner protein WRN with IC50 of 32 nM (WRN ATPase). |
| PC-23728 |
PFM03
MRE11 inhibitor
|
PFM03 is a specific MRE11 endonuclease inhibitor, affects DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ). |
| PC-23727 |
MU147
MRE11 inhibitor
|
MU147 is a specific small molecule inhibitor of MRE11 nuclease with IC50 of 25.3 uM, inhibits MRE11-RAD50-NBS1 (MRN)-dependent homologous recombination. |
| PC-23726 |
MU1409
MRE11 inhibitor
|
MU1409 is a specific small molecule inhibitor of MRE11 nuclease with IC50 of 12.1 uM, inhibits MRE11-RAD50-NBS1 (MRN)-dependent homologous recombination. |
| PC-22774 |
HDGFRP2 PWWP domain inhibitor BBP
HDGFRP2 PWWP inhibitor
|
BBP is a small molecule inhibitor of the hepatoma-derived growth factor-related protein 2 (HDGFRP2) PWWP domain, dually targets both HDGFRP2 and PSIP1 PWWP domains, engage with the aromatic cage of the HDGFRP2 PWWP domain. |
| PC-22697 |
MUS81 inhibitor 24
MUS81 inhibitor
|
MUS81 inhibitor 24 is a small molecule inhibitor of DNA repair endonuclease Mus81 with IC50 of 0.27 uM and SPR Kd of 1.1 uM (MUS81-EME1). |
