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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -NP-004255
NP-004255

Chemical Structure : NP-004255

CAS No.: 23094-69-1

NP-004255 (NP004255;Corilagin)

货号: PC-61922Not For Human Use, Lab Use Only.

NP-004255 (NP004255, Corilagin) is a small molecule binds specifically to DNA repair protein RAD52 and disrupts the RAD52-ssDNA interaction, inhibits ssDNA binding with IC50 of 1.5 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NP-004255 (NP004255, Corilagin) is a small molecule binds specifically to DNA repair protein RAD52 and disrupts the RAD52-ssDNA interaction, inhibits ssDNA binding with IC50 of 1.5 uM.

物理化学性质&存储条件

分子量 634.45
分子式 C27H22O18
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Glucopyranose, cyclic 3,6-(4,4',5,5',6,6'-hexahydroxydiphenate) 1-gallate, β-D- (8CI)

参考文献

1. Hengel SR, et al. Elife. 2016 Jul 19;5. pii: e14740.

2. Hengel SR, et al. Cell Chem Biol. 2017 Sep 21;24(9):1101-1119.

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