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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -HUHS-015
HUHS-015

Chemical Structure : HUHS-015

CAS No.: 1453097-13-6

HUHS-015 (HUHS015)

货号: PC-42079Not For Human Use, Lab Use Only.

HUHS-015 (HUHS015) is a potent, orally active prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with IC50 of 0.67 uM.

规格 价格 库存 数量
25 mg ¥1280 In stock
50 mg ¥1980 In stock
100 mg ¥3480 In stock
500 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

HUHS-015 (HUHS015) is a potent, orally active prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with IC50 of 0.67 uM.
HUHS-015 significantly suppresses the growth of DU145 cells in vitro and in a mouse xenograft model.

物理化学性质&存储条件

分子量 318.3724
分子式 C19H18N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

1H-Pyrazol-5-ol, 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)-

参考文献

1. Nakao S, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1071-4.

2. Mabuchi M, et al. In Vivo. 2015 Jan-Feb;29(1):39-43.

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