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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor

Request The Product List of5-HT Receptor 5-HT Receptor

Cat. No. Product Name Information
PC-63485

SB-258585

5-HT6 antagonist

SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes.
PC-63484

SB-399885 hydrochloride

5-HT6 antagonist

SB-399885 hydrochloride is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors.
PC-63483

SB-399885

5-HT6 antagonist

SB-399885 is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors.
PC-63427

JNJ-5234801

JNJ-5234801 is an atypical anxiolytic targeting 5-HT2 receptor, has demonstrated oral activity in animal models of anxiety..
PC-63401

JNJ-18038683 free base

5-HT7 antagonist

JNJ-18038683 free base is a potent, selective 5-HT7 receptor antagonist with pKi of 8.19 and 8.20 for rat and human 5-HT7 in cell-based assays.
PC-63400

JNJ-18038683

5-HT7 antagonist

JNJ-18038683 is a potent, selective 5-HT7 receptor antagonist with pKi of 8.19 and 8.20 for rat and human 5-HT7 in cell-based assays.
PC-63289

CYD-1-79

5-HT2C PAM

CYD-1-79 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM), potentiates 5-HT-evoked intracellular calcium release in cells stably expressing the human 5-HT2CR but not the 5-HT2AR cells.
PC-63256

DSP-1053

SERT inhibitor, 5-HT1A agonist

DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively.
PC-43401

BRL54443

5-HT1E/1F agonist

BRL54443 is a potent, releative selective 5-HT1E/1F agonist with Ki of 2/1 nM, respectively.
PC-43384

BRL-15572 dihydrochloride

5-HT1D antagonist

BRL-15572 dihydrochloride is a potent, selective h5-HT1D receptor antagonist with pKi of 7.9, dispalys 60-fold selectivity over h5-HT1B.
PC-43382

WAY-100635 maleate

5-HT1A antagonist

WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
PC-43156

Prucalopride succinate

5-HT4 agonist

Prucalopride succinate (R-108512) is a potent, selective 5-HT4 receptor agonist with pKi of 8.6 and 8.1 for 5-HT4a and 5-HT4b, >290-fold higher affinity for 5-HT4 receptors than for other receptors.

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