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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-PZ-1361
PZ-1361

Chemical Structure : PZ-1361

CAS No.: 2095849-69-5

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PZ-1361 (PZ1361)

货号: PC-73305Not For Human Use, Lab Use Only.

PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents.

    物理化学性质&存储条件

    分子量 501.038
    分子式 C26H29ClN2O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(1-(3-([1,1'-biphenyl]-2-yloxy)-2-hydroxypropyl)piperidin-4-yl)-3-chlorobenzenesulfonamide

    参考文献

    1. Vittorio Canale, et al. J Org Chem. 2020 Aug 21;85(16):10958-10965.

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