| Cat. No. |
Product Name |
Information |
| PC-45944 |
Alosetron
5-HT3 antagonist
|
Alosetron (GR-68755) is a potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome. |
| PC-42547 |
WAY-100635
5-HT1A antagonist
|
WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor. |
| PC-42654 |
Ketanserin tartrate
5-HT2A antagonist
|
Ketanserin tartrate (R41468 tartrate) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-42653 |
Ketanserin
5-HT2A antagonist
|
Ketanserin (R41468) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-45229 |
Ziprasidone hydrochloride monohydrate
D2/5-HT2A antagonist
|
Ziprasidone hydrochloride monohydrate (CP-88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-43963 |
Ziprasidone
D2/5-HT2A antagonist
|
Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-27286 |
Alverine citrate
5-HT1A antagonist
|
Alverine citrate is a synthetic derivative of papaverine and selective 5-HT1A receptor antagonist with IC50 of 101 nM, is an antispasmodic agent to alleviate smooth muscle spasms. |
| PC-27115 |
PRX-08066
5-HT2B antagonist
|
PRX-08066 is a potent, selective 5-HT2B receptor (5-HT2BR) antagonist with Ki of 3.4 nM, causes selective vasodilation of pulmonary arteries. |
| PC-27114 |
SB200646
5-HT2B/2C antagonist
|
SB200646 (SB-200646A) is a potent, selective and orally active 5-HT2B/2C receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively, shows electrophysiological and anxiolytic properties. |
| PC-27113 |
YM348
5-HT2C agonist
|
YM348 is a potent, selective and orally active 5-HT2C receptor agonist with Ki of 0.89 nM for cloned human 5-HT(2C) receptor. |
| PC-27112 |
AL-34662
5-HT2A agonist
|
AL-34662 is a potent, selective, and efficacious serotonin-2 (5-HT2) receptor agonist with binding IC50 of 0.8-1.5 nM for rat and human 5-HT2 receptors, and 3-14.5 nM for cloned human 5-HT2A-C receptors. |
| PC-27111 |
RS-127445 hydrochloride
5-HT2B antagonist
|
RS-127445 hydrochloride is a potent, selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with pKi of 9.5, 1,000 fold selectivity over numerous other receptor and ion channel binding sites. |
