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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-RU 24969
RU 24969

Chemical Structure : RU 24969

CAS No.: 66611-26-5

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RU 24969 (RU24969, RU-24969)

货号: PC-45034Not For Human Use, Lab Use Only.

RU 24969 is a potent, selective agonist of 5-HT1A and 5-HT1B receptors with Ki values of 2.5 and 0.38 nM respectively, with preference for 5-HT1B.

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5 mg ￥580 In stock
10 mg ￥880 In stock
50 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

RU 24969 is a potent, selective agonist of 5-HT1A and 5-HT1B receptors with Ki values of 2.5 and 0.38 nM respectively, with preference for 5-HT1B.
RU 24969 inhibited the rate of synthesis of 5-HT in rat brain by about 50% (10mg/kg)

物理化学性质&存储条件

分子量 228.2896
分子式 C14H16N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL
Chemical Name/SMILES

1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-

参考文献

1. Green AR, et al. Neuropharmacology. 1984 Jun;23(6):655-61.

2. Harrison AA, et al. Psychopharmacology (Berl). 1999 Jan;141(3):242-50.

3. Parsons LH, et al. J Neurosci. 1998 Dec 1;18(23):10078-89.

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