Asenapine |CAS:65576-45-6 Probechem Biochemicals

Chemical Structure : Asenapine

CAS No.: 65576-45-6

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Asenapine (Org 5222, Org5222)

货号: PC-42334Not For Human Use, Lab Use Only.

Asenapine (Org5222) is a potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors.

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生物&药学活性

Asenapine (Org5222) is a potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors.
Asenapine shows much lower affinity (pKi<5) for muscarinic receptor.
Asenapine behaves as a potent antagonist 5-HT receptors (5-HT2A pKB=9.0), dopaime and adrenoceptors.
Asenapine shows strong antipsychotic potential in vivo.

物理化学性质&存储条件

分子量	285.768
分子式	C17H16ClNO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, (3aR,12bR)-rel-

参考文献

1. Room P, et al. Eur J Pharmacol. 1991 Dec 3;205(3):233-40.

2. Broekkamp CL, et al. Arzneimittelforschung. 1990 May;40(5):544-9.

3. Frånberg O, et al. Psychopharmacology (Berl). 2008 Feb;196(3):417-29.

4. Shahid M, et al. J Psychopharmacol. 2009 Jan;23(1):65-73.

Asenapine (Org 5222, Org5222)

生物&药学活性

物理化学性质&存储条件

参考文献

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Asenapine (Org 5222, Org5222)

生物&药学活性

物理化学性质&存储条件

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