WAY-100635 | 5-HT1A antagonist | Probechem Biochemicals

Chemical Structure : WAY-100635

CAS No.: 162760-96-5

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WAY-100635 (WAY 100635, WAY100635)

货号: PC-42547Not For Human Use, Lab Use Only.

WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1080	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg	￥4580	In stock
250 mg		Get quote

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生物&药学活性

WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
WAY-100635 completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively.

物理化学性质&存储条件

分子量	422.563
分子式	C25H34N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide

参考文献

1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.

2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.

3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.

WAY-100635 (WAY 100635, WAY100635)

生物&药学活性

物理化学性质&存储条件

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WAY-100635 (WAY 100635, WAY100635)

生物&药学活性

物理化学性质&存储条件

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