Raf (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-26817	LF-268 pan-Raf inhibitor	LF-268 is a potent, selective pan-RAF inhibitor with IC50 of 3.9 nM, 4.0 nM and 1.0 nM for A-Raf, B-Raf and C-Raf respectively.
PC-24277	Braftide RAF dimerization inhibitor	Braftide is a potent allosteric RAF kinase dimer disruptor, inhibits RAF dimerization by targeting the conserved RAF dimer interface, inhibits wild-type BRAF and oncogenic BRAF G469A with IC50 of 364 nM and 172 nM, respectively.
PC-21592	SHR902275 RAFinhibitor	SHR902275 is a potent, selective, and orally active RAF inhibitor targeting RAS mutants with IC50 of 1.6 nM, 10 nM, and 5.7 nM for cRAF, bRAFwt, and bRAFV600E, respectively.

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