SB-590885 |CAS:405554-55-4 Probechem Biochemicals

Chemical Structure : SB-590885

CAS No.: 405554-55-4

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货号: PC-42755Not For Human Use, Lab Use Only.

SB-590885 is a potent and selective B-Raf inhibitor with Kd of 0.3 nM, >1000 fold selectivity over p38a, GSK3b and Lck.

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SB-590885 is a potent and selective B-Raf inhibitor with Kd of 0.3 nM, >1000 fold selectivity over p38a, GSK3b and Lck.

分子量	453.5356
分子式	C27H27N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Inden-1-one, 5-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-, oxime

1. Takle AK, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):378-81.

2. King AJ, et al. Cancer Res. 2006 Dec 1;66(23):11100-5.

3. Villanueva J, et al. Cancer Cell. 2010 Dec 14;18(6):683-95.