| Cat. No. |
Product Name |
Information |
| PC-45524 |
Centrinone B
PLK4 inhibitor
|
Centrinone B (LCR-323) is a selective, reversible PLK4 inhibitor with Ki of 0.6 nM in vitro. |
| PC-45523 |
Centrinone
PLK4 inhibitor
|
Centrinone (LCR-263) is a selective, reversible PLK4 inhibitor with Ki of 0.16 nM in vitro. |
| PC-45884 |
GSK461364
PLK1 inhibitor
|
GSK461364 is a potent, selective, and reversible ATP-competitive PLK1 inhibitor with Ki of 2.2 nM. |
| PC-45847 |
BI-2536
PLK1 inhibitor
|
BI-2536 is a potent and selective inhibitor of PLK1 with IC50 of 0.83 nM. |
| PC-42779 |
GW843682X
PLK1/3 inhibitor
|
GW843682X is a potent and selective inhibitor of PLK1 (IC5=2.2 nM) and PLK3 (IC50=9 nM). |
| PC-25891 |
CZS-089
PLK4 inhibitor
|
CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM. |
| PC-25890 |
CZS-241
PLK4 inhibitor
|
CZS-241 is a potent, selective PLK4 inhibitor with IC50 of 2.6 nM for PLK4, >1000-fold selective over TRKA. |
| PC-25889 |
CZS-034
PLK4 inhibitor
|
CZS-034 is a highly potent. selective PLK4 inhibitor with IC50 of 0.2 nM, exhibits antiproliferative activities against MCF-7, BT474, and MDA-MB-231 cells with IC50 of 0.36, 1.35, and 2.88 uM respectively. |
| PC-25888 |
CZS-035
PLK4 inhibitor
|
CZS-035 is a potent, selective PLK4 inhibitor with binding IC50 of 0.7 nM for PLK4, shows strong antiproliferative activity on MCF-7 cells with IC50 of 0.65 uM. |
| PC-25813 |
TAK-960
PLK1 inhibitor
|
TAK-960 is a potent, selective, ATP-competitive, orally available inhibitor of polo-like kinase 1 (PLK1) with IC50 of 1.6 nM in TR-FRET assays. |
| PC-24920 |
CZL-S092
PLK4 inhibitor
|
CZL-S092 is a potent, selective PLK4 inhibitor with IC50 of 0.9 nM. |
| PC-24600 |
PLK1 inhibitor B4
PLK1 inhibitor
|
PLK1 inhibitor B4 is a novel small molecule inhibitor of polo-like kinase 1 (PLK1) with SPR KD of 5.6 uM, IC50 of 13.52 uM. |
