| Cat. No. |
Product Name |
Information |
| PC-70200 |
MTX-211
PI3K/EGFR inhibitor
|
MTX-211 is a first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with IC50 of <100 nM. |
| PC-60176 |
INCB040093
PI3Kδ inhibitor
|
Dezapelisib (INCB040093) is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 31 nM. |
| PC-60166 |
GDC-0326
PI3Kα inhibitor
|
GDC0326 (GDC-0326) is a potent, selective, orally available PI3Kα inhibitor with Ki of 0.2 nM. |
| PC-70090 |
GSK-2292767
PI3Kδ inhibitor
|
GSK-2292767 is a highly potent and selective inhibitor of PI3Kδ (pKi=10.1). |
| PC-60057 |
Gedatolisib
PI3K/mTOR inhibitor
|
Gedatolisib (PF-05212384, PKI-587) is a highly potent, selective, dual PI3K/mTOR inhibitor with IC50 of 0.4/6/8/6/1.6 nM for PI3Kα/β/γ/δ/mTOR, respectively. |
| PC-45643 |
GSK-2269557
PI3Kδ inhibitor
|
Nemiralisib (GSK-2269557) is a highly potent and selective inhibitor of PI3Kδ (pKi=9.9). |
| PC-45597 |
3-Methyladenine
PI3K inhibitor
|
3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 uM and 60 uM in HeLa cells. |
| PC-45820 |
Pictilisib
PI3K inhibitor
|
Pictilisib (GSC-0941) is a potent, selective, orally bioavailable inhibitor of class I PI3Ks with IC50 of 3/33/3/75 nM for p110α/β/γ/δ, respectively. |
| PC-45782 |
GDC-0941 dimethanesulfonate
PI3K inhibitor
|
Pictilisib dimethanesulfonate (GSC-0941) is a potent, selective, orally bioavailable inhibitor of class I PI3Ks with IC50 of 3/33/3/75 nM for p110α/β/γ/δ, respectively. |
| PC-45950 |
Buparlisib
PI3K inhibitor
|
Buparlisib (NVP-BKM120, BKM-120) is a potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively. |
| PC-44217 |
NVP-BKM120 hydrochloride
PI3K inhibitor
|
NVP-BKM120 (Buparlisib) hydrochloride potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively. |
| PC-45766 |
GDC-0084
PI3K/mTOR inhibitor
|
Paxalisib (GDC-0084, RG7666) is a potent, selective, brain penetrant dual inhibitor of class I PI3Ks and mTOR with Ki of 2/46/3/10/70 nM for PI3Kα/β/δ/γ/mTOR, respectively. |
