| Cat. No. |
Product Name |
Information |
| PC-23003 |
MIPS-19416
PI3K inhibitor
|
MIPS-19416 is a potent dual class I and class II PI3Ks inhibitor with IC50 of 13 nM (PI3KC2α), equal to or more potent than against class I isoforms or against PI3KC2β (IC50=12-94 nM). |
| PC-23002 |
PITCOIN4
PI3KC2α inhibitor
|
PITCOIN4 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 56 nM, >100-fold selectivity over PI3K-C2β. |
| PC-22536 |
TYM-3-98
PI3Kδ inhibitor
|
TYM-3-98 is a potent, selective inhibitor of PI3Kδ (PI3Kdelta) with IC50 of 7.1 nM, highly selective over other PI3K isoforms at both molecular and cellular levels. |
| PC-22090 |
QR-7909
PI3Kα H1047R inhibitor
|
QR-7909 is a potent, specific and allosteric PI3Kα H1047R inhibitor with IC50 of 51 nM, 27-fold selective over WT PI3Kα in biochemical assays. |
| PC-21948 |
PIK-108
p110β inhibitor
|
PIK-108 is a potent, selective and allosteric PI3K p110β inhibitor with IC50 of 57 nM, 45-fold selective over PI3Kα (IC50=2600 nM). |
| PC-21947 |
PI3Kα H1047R inhibitor 17
H1047R PI3Kα inhibitor
|
PI3Kα H1047R inhibitor 17 is a potent, selective H1047R PI3Kα mutant inhibitor with IC50 of 1 nM (inhibition of pAKT formation), without effect on PI3Kα WT. |
| PC-42943 |
TGR-1202 R-enantiomer
|
TGR-1202 R-enantiomer is is the less active enantiomer of TGR-1202 (Umbralisib), TGR-1202 is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 22 nM.. |
| PC-42881 |
PI3K-IN-1
|
PI3K-IN-1 is a potent inhibitor of PI3K, extracted from patent WO2012103524 A2 and WO2013147649 A2.. |
| PC-42647 |
PI3Kγ inhibitor 1
|
A potent PI3Kγ inhibitor.. |
