PDK1 (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofPDK1 PDK1

Cat. No.	Product Name	Information
PC-49261	GSK2334470 PDK1 inhibitor	GSK2334470 (GSK 2334470) is a potent, highly specific inhibitor of PDK1 with IC50 of 10 nM, does not inhibit 93 other protein kinases including 13 AGC-kinases most related to PDK1 at 5 uM.
PC-73258	PDK1 agonist PS48 PDK1 agonist	PDK1 agonist PS48 is a small molecule allosteric phosphoinositide-dependent protein kinase-1 (PDK-1) agonist, PS48 is active at 10 nM to 1 μM in restoring normal insulin-dependent Akt activation and in mitigating Aβi peptide toxicity.
PC-63030	BX-320 PDK1 inhibitor	BX-320 is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 30 nM, >20-fold selectivity over PKA.
PC-62481	PS210 PDK1 actvivator	PS210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1, does not alter the activity of any of the 121 kinases (S6K, PKB/Akt or GSK3).
PC-62480	PS423 PDK1 inhibitor	PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210.
PC-61111	PDK1 inhibitor 7 PDK1 inhibitor	PDK1 inhibitor 7 (MP7) is a potent, selective PDK1 inhibitor with IC50 of 1 nM, displays >3,000-fold selectivity against a panel of 256 kinases.
PC-60606	OSU-03013 PDK1 inhibitor	OSU-03013 (OSU 03013, OSU03013) is a potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) inhibitor with IC50 of 2 uM.
PC-60605	PDK1 inhibitor AR12 PDK1 inhibitor	OSU-03012 (AR12) is a potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) inhibitor with IC50 of 5 uM.
PC-42781	BX-912 PDK1 inhibitor	BX-912 (BX912) is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 26 nM.
PC-42629	BX795 PDK1 inhibitor, TBK1 inhibitor	BX795 is a potent and relatively specific PDK1 inhibitor with IC50 of 6 nM.
PC-21484	CU05-1189 PDK1 inhibitor	CU05-1189 is a non-peptide, allosteric inhibitor of the pleckstrin homology (PH) domain of PDK1, specifically inhibits Akt signaling pathway.

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