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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PDK1-PS210
PS210

Chemical Structure : PS210

CAS No.: 1221962-86-2

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PS210 (PS 210)

货号: PC-62481Not For Human Use, Lab Use Only.

PS210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1, does not alter the activity of any of the 121 kinases (S6K, PKB/Akt or GSK3).

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50 mg ￥3480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PS210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1, does not alter the activity of any of the 121 kinases (S6K, PKB/Akt or GSK3).

物理化学性质&存储条件

分子量 380.319
分子式 C19H15F3O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid

参考文献

1. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14.

2. Busschots K, et al. Chem Biol. 2012 Sep 21;19(9):1152-63.

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