Immune Checkpoints (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofImmune Checkpoints Immune Checkpoints

Cat. No.	Product Name	Information
PC-22944	ICOS inhibitor 9 ICOS/ICOS-L inhibitor	ICOS inhibitor 9 is a small molecule inhibitor of ICOS/ICOS-L interaction with IC50 of 29.38 uM.
PC-21773	CTLA-4 inhibitor A9.1 CTLA-4 inhibitor	CTLA-4 inhibitor A9.1 is a small molecule inhibitor of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) with IC50 of 1.4 uM in AlphaLISA assays.
PC-21772	CTLA-4 inhibitor D11.3 CTLA-4 inhibitor	CTLA-4 inhibitor D11.3 is a small molecule inhibitor of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) with IC50 of 0.97 uM in AlphaLISA assays.
PC-21719	C-5401331 TIM-3 inhibitor	C-5401331 is a small molecule T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor, suppresses acute myeloid leukemia (AML) cell proliferation.
PC-21328	Tim-3 inhibitor ML-T7 TIM-3 inhibitor	Tim-3 inhibitor ML-T7 is a potent small molecule inhibitor of T cell immunoglobulin and mucin-containing molecule 3 (Tim-3), binds to Tim-3 disrupts the interaction of Tim-3 with PtdSer and CEACAM1.
PC-21199	AG-120-X ICOS/ICOSL inhibitor	AG-120-X is a first-in-class small molecule inhibitor of ICOS/ICOSL interaction with IC50 of 4.68 uM in TR-FRET assay, dose-dependently blocks ICOS/ICOSL interaction in cellular assay based on co-culturing Jurkat T cells expressing ICOS and CHO-K1 cells expressing ICOSL.

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