| Cat. No. |
Product Name |
Information |
| PC-72261 |
BRD4 D1 inhibitor 30
BRD4 D1 inhibitor
|
BRD4 D1 inhibitor 30 is a high-affinity, BRD4 D1-selective chemical probe with Kd of 18 nM, 500-fold selectivity against BRD2 D1 and BRD4 D2. |
| PC-72188 |
BY27
BET BD2 inhibitor
|
BY27 (BD2 inhibitor BY27) is a potent, highly selective BET BD2 inhibitor with Ki of 8.9/8.2/14.2 nM for BRD2/3/4-BD2 respectively. |
| PC-72187 |
SJ432
BET BD2 inhibitor
|
SJ432 (SJ-432) is a potent, highly selective BET BD2 inhibitor with Kd of 6/2 nM (BRD2-BD2/BRD4-BD2), displays 80/152-fold selectivity over BD1, respectively. |
| PC-72186 |
SJ018
BET BD2 inhibitor
|
SJ018 (SJ-018) is a potent, highly selective BET BD2 inhibitor with KD of 14 nM (BRD2-BD2), 67-fold selectivity over BRD2-BD1. |
| PC-72185 |
GSK737
BET BD2 inhibitor
|
GSK737 (GSK-737) is a potent, highly selective BET BD2 inhibitor with pIC50 of 7.3 (BRD4 BD2), 200-fold selectivity over BRD4 BD1. |
| PC-72184 |
GSK217
BET BD2 inhibitor
|
GSK217 (GSK-217) is a potent, highly selective BET BD2 inhibitor with pIC50 of 7.5 (BRD4 BD2), 300-fold selectivity over BRD4 BD1. |
| PC-72183 |
GSK852
BET BD2 inhibitor
|
GSK852 (GSK-852) is a highly potent, second bromodomain (BD2)-selective BET inhibitor with pIC50 7.9 (BRD4 BD2), 1260-fold selectivity over BRD4 BD1. |
| PC-72182 |
GSK046
BET BD2 inhibitor
|
GSK046 (GSK-046, iBET-BD2) is a potent, highly selective inhibitor of BET BD2 with pIC50 of 7.3 (BRD4 BD2), >1000-fold over BRD4 BD1. |
| PC-72181 |
GSK040
BET BD2 inhibitor
|
GSK040 (GSK-040) is a potent, highly selective BET BD2 inhibitor with pIC50 of 8.3 (BRD4 BD2), 5000-fold selectivity over BD1. |
| PC-72180 |
GSK549
BET BD2 inhibitor
|
GSK549 (GSK-549) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.8 (BRD4 BD2), 1150-fold selectivity over BD1. |
| PC-72179 |
GSK620
BET BD2 inhibitor
|
GSK620 (GSK-620) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.1 (BRD4 BD2), 220-fold selectivity over BD1. |
| PC-38169 |
NEO2734
CBP/p300-BET inhibitor
|
NEO2734 (NEO-2734, EP31670) is a dual inhibitor of pan-BET and CBP/p300 with Kd values of 2-31 nM. |
