Translocator Protein (TSPO) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofTranslocator Protein (TSPO) Translocator Protein (TSPO)

Cat. No.	Product Name	Information
PC-72081	FGIN-1-27 TSPO agonist	FGIN-1-27 (FGIN 1-27) is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO) with Ki of 5 nM.
PC-62205	Diazepinomicin Ras-RAF-MAPK inhibitor	Diazepinomicin (TLN 4601, ECO-4601) is a brain penetrant inhibitor of Ras-RAF-MAPK pathway post Ras prenylation and prior to MEK activation, binds the central and/or peripheral benzodiazepine receptors (PBR, TSPO).
PC-62197	DPA-714 TSPO ligand	DPA-714 is a potent, selective ligand for the translocator protein (TSPO) with Ki of 7.0 nM.
PC-60733	TSPO agonist CB34 TSPO agonist	TSPO agonist CB34 is a potent, selective translocator protein 18 kDa (TSPO/PBR) agonist with IC50 of 2.59 and 1.03 nM in competing with [3H]-PK11195 for binding to membrane preparations from rat cerebral cortex and ovary, respectively.
PC-60732	ONO-2952 TSPO inhibitor	ONO-2952 is a novel potent, selective, orally active translocator protein 18 kDa (TSPO/PBR) antagonist with Ki of 0.33-9.3 nM for both rat and human TSPO, respectively.
PC-60195	Ro5-4864 TSPO ligand	Ro5-4864 is a potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR).
PC-60185	PK-11195 TSPO ligand	PK-11195 (PK 11195) is an isoquinoline carboxamide that binds selectively to PBR (TSPO) with Ki of 3.1 nM in cerebellum, 4.1 nM in spinal cord.
PC-70052	DAA-1097 TSPO agonist	DAA-1097 is a potent, selective agonist of peripheral benzodiazepine receptor (PBR, TSPO) that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.
PC-45756	DAA-1106 TSPO agonist	DAA-1106 is a potent, selective agonist of PBR/TSPO that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.
PC-22700	XBD173 TSPO agonist	XBD173 (Emapunil, AC-5216) is a selective, orally active 18 kDa translocator protein (TSPO) ligand/agonist, shows antianxiety and antidepressant-like effects.

PREV1NEXT