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首页-小分子抑制剂&激动剂-Others-Translocator Protein (TSPO)-DAA-1097
DAA-1097

Chemical Structure : DAA-1097

CAS No.: 220551-79-1

DAA-1097 (DAA1097, DAA 1097)

货号: PC-70052Not For Human Use, Lab Use Only.

DAA-1097 is a potent, selective agonist of peripheral benzodiazepine receptor (PBR, TSPO) that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DAA-1097 is a potent, selective agonist of peripheral benzodiazepine receptor (PBR, TSPO) that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.

    物理化学性质&存储条件

    分子量 409.904
    分子式 C24H24ClNO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-Chloro-2-phenoxyphenyl)-N-[[2-(1-methylethoxy)phenyl]methyl]acetamide

    参考文献

    1. Okuyama S, et al. Life Sci. 1999;64(16):1455-64.

    2. Okubo T, et al. Bioorg Med Chem. 2004 Jan 15;12(2):423-38.

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